• In white or black polystyrene for luminescence and fluorescence assays • White for a maximum reflection and minimum cross-tack • Black for minimum light scattering and cross-talk • With clear lid • Alphanumeric marking • Flat bottom • Non-pyrogenic, non-cytotoxic • DNAse/RNase free
• 6-well plate with coverslips • In high quality transparent polystyrene • For high-resolution confocal microscopy • Sterile • With lid • Glass coverslips, thickness 133 µm • Cytotoxin-free • Pyrogen free • DNase RNase free • No human DNA
A 3D microenvironment that adapts to the different rigidities and compositions of matrices within tissues and organs. Biomimesys 3D supports are all based on a hyaluronic acid-based hydroskeleton. This hydroskeleton provides a tailor-made support, controlled and physiologically adapted to the cells in which they lie.
Artificial tumours® (3D cultures) from tumour cell lines widely used in oncology • More closely mimics the microenvironment of avascular tumours in vivo than 2D cultures • Increasingly involved in the development of medicines • Ideal study solution for aggressive triple-negative breast cancer
The Opti3D kit® includes artificial tumours® produced in OptiPASS® culture medium in 96-well microplates (one tumour per well) • Transport in anoxia and at 4 °C for dormancy until use (alternative to freezing) • Each microplate includes 100 ml of suitable culture medium (OptiPASS® OPTI03) for in vitro testing
Benefits • Direct use of tumours after deconditioning • Reproducible tumour size and morphology • Guaranteed: less than 10% variation in size within and between microplates • Once deconditioned, resumption of tumour growth for a minimum of 10 days • Available for triple-negative breast cancer, very aggressive subtype: MDA-MB-231 line, SUM1315 line • Ideal for screening, toxicity testing or basic research into mechanisms of interest
• High quality transparent polystyrene • Alphanumeric marking • With transparent lid • USP Class VI • Sterile • Non-cytotoxic • Endotoxin-free • DNase RNase free • Without human DNA • For plates that inhibit all cell adhesion, see the SPL 3D range.
• The configuration of the openings is adapted for a safe position of the drops • The tank prevents evaporation of the medium • Non-cytotoxic • Sterile • No DNase, RNase • Without human DNA • Endotoxin-free